The answer is 72.
The pattern is found by adding the two numbers together and then multiplying that sum by 3.
Here is the pattern applied to each row:
1 + 5 = 18: (1 + 5) = 6 ⇒ 6 × 3 = 18
2 + 7 = 27: (2 + 7) = 9 ⇒ 9 × 3 = 27
3 + 9 = 36: (3 + 9) = 12 ⇒ 12 × 3 = 36
5 + 10 = 45: (5 + 10) = 15 ⇒ 15 × 3 = 45
Following this exact rule for the final equation: